PRODUCTION OF DIRECTLY COMPRESSIBLE EXCIPIENTS WITH MANNITOL BY WET GRANULATION: RHEOLOGICAL, COMPRESSIBILITY AND COMPACTIBILITY CHARACTERIZATION
نویسندگان
چکیده
منابع مشابه
A study of compressibility and compactibility of directly compressible tableting materials containing tramadol hydrochloride.
The paper evaluates and compares the compressibility and compactibility of directly compressible tableting materials for the preparation of hydrophilic gel matrix tablets containing tramadol hydrochloride and the coprocessed dry binders Prosolv® SMCC 90 and Disintequik™ MCC 25. The selected types of hypromellose are Methocel™ Premium K4M and Methocel™ Premium K100M in 30 and 50 % concentrations...
متن کاملA review of co-processed directly compressible excipients.
Direct compression is the preferred method for the preparation of tablets. The present review outlines the importance of the functionality of the directly compressible adjuvants in the formulation of tablets. The co-processing is the most widely explored method for the preparation of directly compressible adjuvants because it is cost effective and can be prepared in-house based on the functiona...
متن کاملEffect of Reprocessing and Excipient Characteristics on Ibuprofen Tablet Properties
Purpose: To determine excipient and ibuprofen:excipient mixture sensitivity to reprocessing produced by either direct compression or wet granulation. Methods: The effect of excipient type, technology and reprocessing on flow, compressibility and compactibility was assessed using and 8x2x2 factorial design. Design Expert® v.8.01 software was employed for data analysis. Pure excipients were proce...
متن کاملStudies on Flowability, Compressibility and In-vitro release of Terminalia Chebula Fruit Powder Tablets
The dried fruit of Terminalia chebula is widely used for its laxative properties. The objective of the present study was to examine the flowability and compressibility of Terminalia chebula fruit powder, subsequently developing its tablet formulations by utilizing wet granulation and direct compression technology. Initial studies on flowability and compressibility revealed that the fruit powder...
متن کاملStudies on Flowability, Compressibility and In-vitro Release of Terminalia Chebula Fruit Powder Tablets
The dried fruit of Terminalia chebula is widely used for its laxative properties. The objective of the present study was to examine the flowability and compressibility of Terminalia chebula fruit powder, subsequently developing its tablet formulations by utilizing wet granulation and direct compression technology. Initial studies on flowability and compressibility revealed that the fruit powder...
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ژورنال
عنوان ژورنال: FARMACIA
سال: 2019
ISSN: 0014-8237
DOI: 10.31925/farmacia.2019.6.7